Testing scientific models using Qualitative Reasoning: Application to cellulose hydrolysis.

ABSTRACT: With the accumulation of scientific information in natural science, even experts can find difficult to keep integrating new piece of information. It is critical to explore modelling solutions able to capture information scattered in publications as a computable representation form. Traditional modelling techniques are important in that regard, but relying on numerical information comes with limitations for integrating results from distinct studies, high-level representations can be more suited. We present an approach to stepwise construct mechanistic explanation from selected scientific papers using the Qualitative Reasoning framework. As a proof of concept, we apply the approach to modelling papers about cellulose hydrolysis mechanism, focusing on the causal explanations for the decreasin

SUBMITTER: Kansou K 

PROVIDER: S-EPMC5658447 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature