Polyhydroxyalkanoate-associated phasins as phylogenetically heterogeneous, multipurpose proteins.

ABSTRACT: Polyhydroxyalkanoates (PHAs) are natural polyesters of increasing biotechnological importance that are synthesized by many prokaryotic organisms as carbon and energy storage compounds in limiting growth conditions. PHAs accumulate intracellularly in form of inclusion bodies that are covered with a proteinaceous surface layer (granule-associated proteins or GAPs) conforming a network-like surface of structural, metabolic and regulatory polypeptides, and configuring the PHA granules as complex and well-organized subcellular structures that have been designated as 'carbonosomes'. GAPs include several enzymes related to PHA metabolism (synthases, depolymerases and hydroxylases) together with the so-called phasins, an heterogeneous group of small-size proteins that cover most of the PHA granule

SUBMITTER: Maestro B 

PROVIDER: S-EPMC5658603 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature