Functional evaluation of sublingual microcirculation indicates successful weaning from VA-ECMO in cardiogenic shock.

ABSTRACT:

Background

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly adopted for the treatment of cardiogenic shock (CS). However, a marker of successful weaning remains largely unknown. Our hypothesis was that successful weaning is associated with sustained microcirculatory function during ECMO flow reduction. Therefore, we sought to test the usefulness of microcirculatory imaging in the same sublingual spot, using incident dark field (IDF) imaging in assessing successful weaning from VA-ECMO and compare IDF imaging with echocardiographic parameters.

Methods

Weaning was performed by decreasing the VA-ECMO flow to 50% (F₅₀) from the baseline. The endpoint of the study was successful VA-ECMO explantation within 48 hours after weaning. The response

SUBMITTER: Akin S 

PROVIDER: S-EPMC5658964 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature