The applicability of a weight loss grading system in cancer cachexia: a longitudinal analysis.

ABSTRACT:

Background

A body mass index (BMI) adjusted weight loss grading system (WLGS) is related to survival in patients with cancer. The aim of this study was to examine the applicability of the WLGS by confirming its prognostic validity, evaluating its relationship to cachexia domains, and exploring its ability to predict cachexia progression.

Methods

An international, prospective observational study of patients with incurable cancer was conducted. For each patient, weight loss grade was scored 0-4. Weight loss grade 0 represents a high BMI with limited weight loss, progressing through to weight loss grade 4 representing low BMI and a high degree of weight loss. Survival analyses were used to confirm prognostic validity. Analyses of variance were used to evaluate the relationship

SUBMITTER: Vagnildhaug OM 

PROVIDER: S-EPMC5659057 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature