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The Macronuclear Genome of Stentor coeruleus Reveals Tiny Introns in a Giant Cell.


ABSTRACT: The giant, single-celled organism Stentor coeruleus has a long history as a model system for studying pattern formation and regeneration in single cells. Stentor [1, 2] is a heterotrichous ciliate distantly related to familiar ciliate models, such as Tetrahymena or Paramecium. The primary distinguishing feature of Stentor is its incredible size: a single cell is 1 mm long. Early developmental biologists, including T.H. Morgan [3], were attracted to the system because of its regenerative abilities-if large portions of a cell are surgically removed, the remnant reorganizes into a normal-looking but smaller cell with correct proportionality [2, 3]. These biologists were also drawn to Stentor because it exhibits a rich repertoire of behaviors, including light avoidance, mechanosensitive contra

SUBMITTER: Slabodnick MM 

PROVIDER: S-EPMC5659724 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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