Whole-genome assembly of Babesia ovata and comparative genomics between closely related pathogens.

ABSTRACT:

Background

Babesia ovata, belonging to the phylum Apicomplexa, is an infectious parasite of bovids. It is not associated with the manifestation of severe symptoms, in contrast to other types of bovine babesiosis caused by B. bovis and B. bigemina; however, upon co-infection with Theileria orientalis, it occasionally induces exacerbated symptoms. Asymptomatic chronic infection in bovines is usually observed only for B. ovata. Comparative genomic analysis could potentially reveal factors involved in these distinguishing characteristics; however, the genomic and molecular basis of these phenotypes remains elusive, especially in B. ovata. From a technical perspective, the current development of a very long read sequencer, MinION, will facilitate the obtainment of highly integrated geno

SUBMITTER: Yamagishi J 

PROVIDER: S-EPMC5660447 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature