Optic Disc Image Subtraction as an Aid to Detect Glaucoma Progression.

ABSTRACT:

Purpose

To present a digital image subtraction technique to alert clinicians to signs of glaucomatous optic disc progression.

Methods

Ninety-two glaucomatous eyes (65 patients) were included. Thirty-three eyes were identified as progressive and 59 as stable based on comparison of baseline and follow-up stereoscopic disc photographs by three masked glaucoma specialists. The disc images were aligned and converted to gray scale and underwent histogram matching to enhance contrast and account for illumination differences. The difference in image intensity between baseline and follow-up images was shown as a colormap superimposed on the grayscale follow-up image. A graded scale (1, no progression, to 5, definitive progression) was used by three masked glaucoma experts to score pr

SUBMITTER: Amini N 

PROVIDER: S-EPMC5661381 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature