Residential road traffic noise exposure and colorectal cancer survival - A Danish cohort study.

ABSTRACT:

Background

Residential traffic noise exposure may entail sleep disruption and compromised circadian functioning; two factors which have been associated with a poor colorectal cancer (CRC) prognosis. Hence, the aim of the present study was to investigate the association between residential road traffic noise and CRC survival.

Methods and materials

Road traffic noise was calculated for all residential addresses from 1987 to February 2012 for incident CRC cases (n = 1,234) in a cohort of 57,053 Danes. We used Cox Proportional Hazard Models to investigate the association between residential road traffic noise at different time-windows, and overall and CRC-specific mortality. Furthermore, we investigated interaction with sex, age, prognostic factors, and comorbidity. Mortality Ra

SUBMITTER: Roswall N 

PROVIDER: S-EPMC5662233 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature