The molecular epidemiology of respiratory viruses associated with asthma attacks: A single-center observational study in Japan.

ABSTRACT: Few reports have described the significance of viral respiratory infections (VRIs) in exacerbation of asthma in adult patients. The aim of this study was to elucidate the profiles of VRIs in adult patients with asthma along with their molecular epidemiology.A cross-sectional observational study was conducted at Kyorin University Hospital from August 2012 to May 2015. To identify respiratory pathogens in inpatients and outpatients suffering from asthma attacks, RT-PCR/sequencing/phylogenetic analysis methods were applied alongside conventional microbiological methods. Phylogenetic and pairwise distance analyses of 10 viruses were performed.A total of 106 asthma attack patients enrolled in this study in both inpatient (n = 49) and outpatient (n = 57) settings. The total 106 respiratory sampl

SUBMITTER: Saraya T 

PROVIDER: S-EPMC5662372 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature