Thirty Years of Sweat Chloride Testing at One Referral Center.

ABSTRACT:

Objective

To conduct a descriptive analysis of the sweat test (ST), associating ST results with epidemiological data, CFTR (cystic fibrosis transmembrane conductance regulator) mutations and reasons to indicate the ST, as well as correlating sweat sodium and sweat chloride concentrations in subjects.

Methods

Retrospective survey and descriptive analysis of 5,721 ST at a university referral center.

Results

The inclusion of the subjects was based on clinical data related with cystic fibrosis (CF) phenotype. The samples were grouped by (i) sweat chloride concentrations (mEq/L): <30: 3,249/5,277 (61.6%); ≥30 to <60: 1,326/5,277 (25.1%); ≥60: 702/5,277 (13.3%) and (ii) age: (Group A--GA) 0 to <6 months; (Group B--GB) ≥6 months to <18 years; (Group C--GC) ≥18 years.

SUBMITTER: Faria AG 

PROVIDER: S-EPMC5662556 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature