Ontology highlight
ABSTRACT:
SUBMITTER: Vallecillo-Garcia P
PROVIDER: S-EPMC5662571 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Nature communications 20171031 1
Fibro-adipogenic progenitors (FAPs) are an interstitial cell population in adult skeletal muscle that support muscle regeneration. During development, interstitial muscle connective tissue (MCT) cells support proper muscle patterning, however the underlying molecular mechanisms are not well understood and it remains unclear whether adult FAPs and embryonic MCT cells share a common lineage. We show here that mouse embryonic limb MCT cells expressing the transcription factor Osr1, differentiate in ...[more]