The Gene-Diet Associations in Postmenopausal Women with Newly Diagnosed Dyslipidemia.

ABSTRACT:

Objectives

The aim of this study was to determine the relationship between polymorphisms of peroxisome proliferator activated receptor - PPAR gamma-2 (Pro12Ala, C1431T) and beta 3-adrenergic receptor - ADRB3 (Trp64Arg) and dietary habits in a group of postmenopausal women who were not under hypolipidemic treatment.

Design

Genetic, nutritional and anthropometric parameters were measured in 213 dyslipidemic (LDL ≥115 mg/dL) and 58 normolipidemic (LDL<115) postmenopausal women. The PCR-RFLP method were used to determine the distributions of selected alleles and genotype frequencies. Dietary intake of basic components and fatty acids was obtained from a 7-day weighed food record and the bio-impedance method was used to determine nutritional status.

Results

Nearly 79% of a

SUBMITTER: Grygiel-Gorniak B 

PROVIDER: S-EPMC5662705 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature