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Septicemia is associated with increased risk for dementia: a population-based longitudinal study.


ABSTRACT:

Background

Systemic infection has been linked to cognitive impairment. We hypothesized that patients with septicemia are predisposed to increased risks for developing dementia in a long-term setting.

Methods

This observational, retrospective, longitudinal, nation-wide population-based study was conducted using the data deduced from Longitudinal Health Insurance Database (LHID) in Taiwan. All patients with septicemia hospitalized for the first time from 2001 to 2011 without prior dementia were included. The development of Alzheimer's disease (AD) or non-Alzheimer dementias (NAD) in relation to the development of septicemia for each patient was recorded. An age- and sex-matched cohort without septicemia and without prior dementia served as the control. Septicemia, dementia, an

SUBMITTER: Chou CH 

PROVIDER: S-EPMC5663596 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature