Prognostic value of bone scan index as an imaging biomarker in metastatic prostate cancer: a meta-analysis.

ABSTRACT:

Background

The prognostic value of the bone scan index (BSI) in metastatic prostate cancer (mPCa) remained controversial. Therefore, we performed a meta-analysis to determine the predictive value of BSI and survival in patients with mPCa.

Materials and methods

A literature search was performed in PubMed, Embase, Web of Science and Cochrane library databases. Hazard ratios (HRs), concordance indices (C-indices) were extracted to estimate the relationship between BSI and survival in patients with mPCa. Subgroup analyses were conducted on different types of mPCa, ethnics, cut-off values and sample sizes.

Results

14 high quality studies involving 1295 patients with mPCa were included in this meta-analysis. The pooled results indicated that high basline BSI and elevated BS

SUBMITTER: Li D 

PROVIDER: S-EPMC5663610 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature