Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats.
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ABSTRACT:
SUBMITTER: Stringhetta-Garcia CT
PROVIDER: S-EPMC5663961 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
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Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats.
Stringhetta-Garcia Camila Tami CT Morais Samuel Rodrigues Lourenço SRL Fernandes Fernanda F Perez-Ueno Melise Jacon MJ Almeida Ricardo de Paula RP Louzada Mário Jefferson Quirino MJQ Chaves-Neto Antonio Hernandes AH Ervolino Edilson E Dornelles Rita Cássia Menegati RCM
Scientific reports 20171031 1
The aim of this study was to prevent female osteoporosis using strength training (ST), raloxifene (Ral) or a combination of ST plus Ral during the natural female aging process, specifically in the periestropause period. For a total of 120 days, aging female Wistar rats at 18-21 months of age performed ST on a ladder three times per week, and Ral was administered daily by gavage (1 mg/kg/day). Bone microarchitecture, areal bone mineral density, bone strength of the femoral neck, immunohistochemis ...[more]
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