Heat Resistance Mediated by pLM58 Plasmid-Borne ClpL in Listeria monocytogenes.

ABSTRACT: Listeria monocytogenes is one of the most heat-resistant non-spore-forming food-borne pathogens and poses a notable risk to food safety, particularly when mild heat treatments are used in food processing and preparation. While general heat stress properties and response mechanisms of L. monocytogenes have been described, accessory mechanisms providing particular L. monocytogenes strains with the advantage of enhanced heat resistance are unknown. Here, we report plasmid-mediated heat resistance of L. monocytogenes for the first time. This resistance is mediated by the ATP-dependent protease ClpL. We tested the survival of two wild-type L. monocytogenes strains-both of serotype 1/2c, sequence type ST9, and high sequence identity-at high temperatures and compared their genome composition in o

SUBMITTER: Pontinen A 

PROVIDER: S-EPMC5663981 | biostudies-literature | 2017 Nov-Dec

REPOSITORIES: biostudies-literature