Ontology highlight
ABSTRACT:
SUBMITTER: Barh D
PROVIDER: S-EPMC5664095 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Barh Debmalya D García-Solano María E ME Tiwari Sandeep S Bhattacharya Antaripa A Jain Neha N Torres-Moreno Daniel D Ferri Belén B Silva Artur A Azevedo Vasco V Ghosh Preetam P Blum Kenneth K Conesa-Zamora Pablo P Perry George G
Genes 20170928 10
The Transcription factor BarH like homeobox 1 (BARHL1) is overexpressed in medulloblastoma and plays a role in neurogenesis. However, much about the BARHL1 regulatory networks and their functions in neurodegenerative and neoplastic disorders is not yet known. In this study, using a tissue microarray (TMA), we report for the first time that BARHL1 is downregulated in hormone-negative breast cancers and Alzheimer's disease (AD). Furthermore, using an integrative bioinformatics approach and mining ...[more]