Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores.

ABSTRACT:

Objective

To explore the association between metabolic syndrome and the Unified Parkinson's Disease Rating Scale (UPDRS) scores and, secondarily, the Symbol Digit Modalities Test (SDMT).

Methods

This is a secondary analysis of data from 1,022 of 1,741 participants of the National Institute of Neurological Disorders and Stroke Exploratory Clinical Trials in Parkinson Disease Long-Term Study 1, a randomized, placebo-controlled trial of creatine. Participants were categorized as having or not having metabolic syndrome on the basis of modified criteria from the National Cholesterol Education Program Adult Treatment Panel III. Those who had the same metabolic syndrome status at consecutive annual visits were included. The change in UPDRS and SDMT scores from randomization to 3 ye

SUBMITTER: Leehey M 

PROVIDER: S-EPMC5664310 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature