Insomnia and risk of nonalcoholic fatty liver disease: A systematic review and meta-analysis.

ABSTRACT:

Aim

This sudy aims to investigate the association between insomnia or excessive daytime sleepiness (EDS) and risk of nonalcoholic fatty liver disease (NAFLD).

Methods

We searched published studies indexed in MEDLINE and EMBASE database from inception to December 2015. Studies that reported odds ratios (ORs), risk ratios, hazard ratios or standardized incidence ratio with 95% confidence intervals (CI) comparing the risk of NAFLD among participants who had insomnia or EDS versus those without insomnia or EDS were included. Pooled ORs and 95% CI were calculated using a random-effect, generic inverse variance method of DerSimonian and Laird. Cochran's Q test and I2 statistic were used to determine the between-study heterogeneity.

Results

Our search strategy yielded 2117 p

SUBMITTER: Wijarnpreecha K 

PROVIDER: S-EPMC5664866 | biostudies-literature | 2017 Oct-Dec

REPOSITORIES: biostudies-literature