High-dose versus low-dose haemofiltration for the treatment of critically ill patients with acute kidney injury: an updated systematic review and meta-analysis.

ABSTRACT:

Objective

The purpose of this study was to perform a systematic review and meta-analysis to evaluate the effect of high-dose versus low-dose haemofiltration on the survival of critically ill patients with acute kidney injury (AKI). We hypothesised that high-dose treatments are not associated with a higher risk of mortality.

Design

Meta-analysis.

Setting

Randomised controlled trials and two-arm prospective and retrospective studies were included.

Participants

Critically ill patients with AKI.

Interventions

Continuous renal replacement therapy.

Primary and secondary outcome measures

Primary outcomes: 90-day mortality, intensive care unit (ICU) mortality, hospital mortality; secondary outcomes: length of ICU and hospital stay.

Result

Eight stu

SUBMITTER: Li P 

PROVIDER: S-EPMC5665234 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature