Forensic Human Identification Using Skin Microbiomes.

ABSTRACT: The human microbiome contributes significantly to the genetic content of the human body. Genetic and environmental factors help shape the microbiome, and as such, the microbiome can be unique to an individual. Previous studies have demonstrated the potential to use microbiome profiling for forensic applications; however, a method has yet to identify stable features of skin microbiomes that produce high classification accuracies for samples collected over reasonably long time intervals. A novel approach is described here to classify skin microbiomes to their donors by comparing two feature types: Propionibacterium acnes pangenome presence/absence features and nucleotide diversities of stable clade-specific markers. Supervised learning was used to attribute skin microbiomes from 14 sk

SUBMITTER: Schmedes SE 

PROVIDER: S-EPMC5666146 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature