Predicting Amyloidogenic Proteins in the Proteomes of Plants.

ABSTRACT: Amyloids are protein fibrils with characteristic spatial structure. Though amyloids were long perceived to be pathogens that cause dozens of incurable pathologies in humans and mammals, it is currently clear that amyloids also represent a functionally important form of protein structure implicated in a variety of biological processes in organisms ranging from archaea and bacteria to fungi and animals. Despite their social significance, plants remain the most poorly studied group of organisms in the field of amyloid biology. To date, amyloid properties have only been demonstrated in vitro or in heterologous systems for a small number of plant proteins. Here, for the first time, we performed a comprehensive analysis of the distribution of potentially amyloidogenic proteins in the proteomes o

SUBMITTER: Antonets KS 

PROVIDER: S-EPMC5666836 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature