The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial.

ABSTRACT: Objective: To examine the potential influence of chronic inflammation on peripheral motor nerve function in vivo following spinal cord injury (SCI). Methods: This study was part of a randomized, parallel-group, controlled clinical trial. The study included 20 participants with varying levels and severities of SCI randomized (3:2) to either a treatment group, consisting of a 12-week anti-inflammatory diet program, or control group. Outcome measures were assessed at baseline, 1 month, and 3 months and consisted of measures of motor nerve conduction velocity (NCV) and amplitude as well as markers of inflammation as assessed by various pro- and anti-inflammatory cytokines. Results: Despite a significant reduction in inflammation in the treatment group, 2-way repeated measu

SUBMITTER: Allison DJ 

PROVIDER: S-EPMC5667434 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature