A core outcome set for adult cardiac surgery trials: A consensus study.

ABSTRACT:

Background

Invasive off- or on-pump cardiac surgery (elective and emergency procedures, excluding transplants are routinely performed to treat complications of ischaemic heart disease. Randomised controlled trials (RCT) evaluate the effectiveness of treatments in the setting of cardiac surgery. However, the impact of RCTs is weakened by heterogeneity in outcome measuring and reporting, which hinders comparison across trials. Core outcome sets (COS, a set of outcomes that should be measured and reported, as a minimum, in clinical trials for a specific clinical field) help reduce this problem. In light of the above, we developed a COS for cardiac surgery effectiveness trials.

Methods

Potential core outcomes were identified a priori by analysing data on 371 RCTs of 58,253 patie

SUBMITTER: Benstoem C 

PROVIDER: S-EPMC5667757 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature