Evaluating the contribution of gut microbiome to the variance of porcine serum glucose and lipid concentration.

ABSTRACT: Serum glucose and lipids are important indicators for host metabolic condition. Interaction of host and gut microbes regulates the metabolism process. However, how much the gut microbiome contributes to the variance of serum glucose and lipids is largely unknown. Here we carried out a 16S rRNA gene based association study between cecum microbiome and the concentration of serum glucose and lipids in 240 Chinese Erhualian pigs. We identified tens of bacterial taxa associated with serum glucose and lipids. The butyrate-producing bacteria were significantly associated with serum glucose level. The pathogenic bacteria belonging to Proteobacteria and Fusobacteria showed significant associations with increased serum lipid levels, while the bacteria Lactobacillus and Bacilli had negative correlati

SUBMITTER: Huang X 

PROVIDER: S-EPMC5668236 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature