Evaluation of ablation catheter technology: Comparison between thigh preparation model and an in vivo beating heart.

ABSTRACT:

Background

An in vivo animal thigh model is the standard technique for evaluation of ablation catheter technologies, including efficacy and safety of ablation. However, the biophysics of ablation in a thigh model may not be similar to a beating heart.

Objective

The purpose of this study was to compare efficacy and safety of ablation between a thigh preparation model and a beating heart.

Methods

In 7 swine, radiofrequency ablation using a 3.5-mm open irrigated catheter (ThermoCool Smart Touch) was performed sequentially in a thigh muscle and in vivo beating ventricles. Ablation was performed at low (30 W for 40 s) and high (40 W for 60 s) energy settings and at similar contact force. Ablation lesions were scanned in high resolution and measured using electronic caliper

SUBMITTER: Leshem E 

PROVIDER: S-EPMC5669034 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature