Fully automated atlas-based method for prescribing 3D PRESS MR spectroscopic imaging: Toward robust and reproducible metabolite measurements in human brain.

ABSTRACT:

Purpose

To implement a fully automated atlas-based method for prescribing 3D PRESS MR spectroscopic imaging (MRSI).

Methods

The PRESS selected volume and outer-volume suppression bands were predefined on the MNI152 standard template image. The template image was aligned to the subject T₁ -weighted image during a scan, and the resulting transformation was then applied to the predefined prescription. To evaluate the method, H-1 MRSI data were obtained in repeat scan sessions from 20 healthy volunteers. In each session, datasets were acquired twice without repositioning. The overlap ratio of the prescribed volume in the two sessions was calculated and the reproducibility of inter- and intrasession metabolite peak height and area ratios was measured by the coefficient

SUBMITTER: Bian W 

PROVIDER: S-EPMC5670025 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature