Expression of adiponectin in the subchondral bone of lumbar facet joints with different degrees of degeneration.

ABSTRACT:

Background

Osteoarthritis research has been most commonly performed in the setting of the articular cartilage of the knee. To the best of our knowledge, no studies have evaluated the role of adiponectin in osteoarthritis of the lumbar facet joint (FJOA). Therefore, in this study, we explored whether adiponectin was expressed in the lumbar facet joints and evaluated the role of adiponectin in FJOA.

Methods

We enrolled patients who underwent lumbar computed tomography (CT) and magnetic resonance imaging (MRI) at the Orthopedic Department of the First Affiliated Hospital of Nanchang from May 2015 to June 2016. Lumbar facet joints were obtained from 135 patients at the time of lumbar fusion surgery and divided into three groups according to the Weishaupt grade. Cytokine levels i

SUBMITTER: Lai Q 

PROVIDER: S-EPMC5670694 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature