A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.

ABSTRACT: Scavenger receptors constitute a large family of proteins that are structurally diverse and participate in a wide range of biological functions. These receptors are expressed predominantly by myeloid cells and recognize a diverse variety of ligands including endogenous and modified host-derived molecules and microbial pathogens. There are currently eight classes of scavenger receptors, many of which have multiple names, leading to inconsistencies and confusion in the literature. To address this problem, a workshop was organized by the United States National Institute of Allergy and Infectious Diseases, National Institutes of Health, to help develop a clear definition of scavenger receptors and a standardized nomenclature based on that definition. Fifteen experts in the scavenger receptor f

SUBMITTER: PrabhuDas MR 

PROVIDER: S-EPMC5671342 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature