Role of early second-trimester uterine artery Doppler screening to predict small-for-gestational-age babies in nulliparous women.

ABSTRACT:

Background

Trophoblastic invasion of the uterine spiral arteries substantially increases compliance to accommodate increased blood flow to the placenta. Failure of this process impedes uterine artery blood flow, and this may be detected by uterine artery Doppler flow studies. However, the clinical utility of uterine artery Doppler flow studies in the prediction of adverse pregnancy outcomes in a general population remains largely unknown.

Objective

We sought to determine the utility of early second-trimester uterine artery Doppler studies as a predictor of small-for-gestational-age neonates.

Study design

Nulliparous women with a viable singleton pregnancy were recruited during their first trimester into an observational prospective cohort study at 8 institutions acros

SUBMITTER: Parry S 

PROVIDER: S-EPMC5671346 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature