Multimodal MR Imaging Signatures of Cognitive Impairment in Active Professional Fighters.

ABSTRACT: Purpose To investigate whether combining multiple magnetic resonance (MR) imaging modalities such as T1-weighted and diffusion-weighted MR imaging could reveal imaging biomarkers associated with cognition in active professional fighters. Materials and Methods Active professional fighters (n = 297; 24 women and 273 men) were recruited at one center. Sixty-two fighters (six women and 56 men) returned for a follow-up examination. Only men were included in the main analysis of the study. On the basis of computerized testing, fighters were separated into the cognitively impaired and nonimpaired groups on the basis of computerized testing. T1-weighted and diffusion-weighted imaging were performed, and volume and cortical thickness, along with diffusion-derived metrics of 20 major white matter tr

SUBMITTER: Mishra VR 

PROVIDER: S-EPMC5673052 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature