Association between biomarkers and clinical characteristics in chronic subdural hematoma patients assessed with lasso regression.

ABSTRACT: Chronic subdural hematoma (CSDH) is characterized by an "old" encapsulated collection of blood and blood breakdown products between the brain and its outermost covering (the dura). Recognized risk factors for development of CSDH are head injury, old age and using anticoagulation medication, but its underlying pathophysiological processes are still unclear. It is assumed that a complex local process of interrelated mechanisms including inflammation, neomembrane formation, angiogenesis and fibrinolysis could be related to its development and propagation. However, the association between the biomarkers of inflammation and angiogenesis, and the clinical and radiological characteristics of CSDH patients, need further investigation. The high number of biomarkers compared to the number of observa

SUBMITTER: Pripp AH 

PROVIDER: S-EPMC5673201 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature