Functional dissection of signal and noise in MT and LIP during decision-making.

ABSTRACT: During perceptual decision-making, responses in the middle temporal (MT) and lateral intraparietal (LIP) areas appear to map onto theoretically defined quantities, with MT representing instantaneous motion evidence and LIP reflecting the accumulated evidence. However, several aspects of the transformation between the two areas have not been empirically tested. We therefore performed multistage systems identification analyses of the simultaneous activity of MT and LIP during individual decisions. We found that monkeys based their choices on evidence presented in early epochs of the motion stimulus and that substantial early weighting of motion was present in MT responses. LIP responses recapitulated MT early weighting and contained a choice-dependent buildup that was distinguishable from mo

SUBMITTER: Yates JL 

PROVIDER: S-EPMC5673485 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature