Evidence for differential opioid use disorder in schizophrenia in an addiction treatment population.

ABSTRACT: Although people diagnosed with schizophrenia are known to have elevated risks of abuse and dependence for nicotine, alcohol, cocaine, and cannabis, it is less clear if schizophrenia is associated with higher rates of opioid use disorders compared to either the general population or individuals with other major psychiatric disorders. Here we examine a large publicly available database from substance abuse treatment centers to compare how frequently patients with schizophrenia report problems with heroin or other opioid drugs compared to other major drugs of abuse. For comparison, the pattern of substance abuse in schizophrenia is contrasted with individuals with major depression, bipolar disorder, and the entire sample of individuals seeking substance abuse treatment. We find that a signifi

SUBMITTER: Chiappelli J 

PROVIDER: S-EPMC5673592 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature