Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility.

ABSTRACT: The use of ozone (O₃) gas as a therapy in alternative medicine has attracted skepticism due to its unstable molecular structure. However, copious volumes of research have provided evidence that O₃'s dynamic resonance structures facilitate physiological interactions useful in treating a myriad of pathologies. Specifically, O₃ therapy induces moderate oxidative stress when interacting with lipids. This interaction increases endogenous production of antioxidants, local perfusion, and oxygen delivery, as well as enhances immune responses. We have conducted a comprehensive review of O₃ therapy, investigating its contraindications, routes and concentrations of administration, mechanisms of action, disinfectant properties in various microorganisms, and

SUBMITTER: Smith NL 

PROVIDER: S-EPMC5674660 | biostudies-literature | 2017 Jul-Sep

REPOSITORIES: biostudies-literature