Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study.

ABSTRACT:

Objective

Neuroimaging studies revealed the functional reorganization or the structural changes during stroke recovery. However, previous studies did not combine the functional and structural information and the results might be affected by heterogeneous lesion. This study aimed to investigate functional activation-informed structural changes during stroke recovery.

Methods

MRI data of twelve stroke patients were collected at four consecutive time points during the first 3 months after stroke onset. Functional activation during finger-tapping task was used to inform the analysis of structural changes of activated brain regions. Correlation between structural changes in motor-related activated brain regions and motor function recovery was estimated.

Results

The average

SUBMITTER: Wu Z 

PROVIDER: S-EPMC5674725 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature