Linking left hemispheric tissue preservation to fMRI language task activation in chronic stroke patients.

ABSTRACT: The preservation of near-typical function in distributed brain networks is associated with less severe deficits in chronic stroke patients. However, it remains unclear how task-evoked responses in networks that support complex cognitive functions such as semantic processing relate to the post-stroke brain anatomy. Here, we used recently developed methods for the analysis of multimodal MRI data to investigate the relationship between regional tissue concentration and functional MRI activation evoked during auditory semantic decisions in a sample of 43 chronic left hemispheric stroke patients and 43 age, handedness, and sex-matched controls. Our analyses revealed that closer-to-normal levels of tissue concentration in left temporo-parietal cortex and the underlying white matter correlated wi

SUBMITTER: Griffis JC 

PROVIDER: S-EPMC5675757 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature