Skeletal Muscle Fat and Its Association With Physical Function in Rheumatoid Arthritis.

ABSTRACT:

Objective

To characterize skeletal muscle fat (SMF), intermuscular adipose tissue (IMAT), and subcutaneous adipose tissue (SAT) in individuals with rheumatoid arthritis (RA), and assess the associations between these fat depots and physical function and physical activity.

Methods

In a cross-sectional analysis from an RA cohort, SMF, IMAT, and SAT were measured using computed tomography imaging of the midthigh cross-sectional region. Physical function was measured using the Health Assessment Questionnaire (HAQ) and a battery of performance-based tests that included quadriceps muscle strength, gait speed, repeated chair-stands, stair ascent, and single-leg stance. Physical activity was assessed using an activity monitor. Associations between SMF, IMAT, and SAT and physical fun

SUBMITTER: Khoja SS 

PROVIDER: S-EPMC5677587 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature