Bespoke Diblock Copolymer Nanoparticles Enable the Production of Relatively Stable Oil-in-Water Pickering Nanoemulsions.

ABSTRACT: Sterically stabilized diblock copolymer nanoparticles with an intensity-average diameter of 25 nm are prepared in the form of a concentrated aqueous dispersion using polymerization-induced self-assembly (PISA). The addition of n-dodecane followed by high-shear homogenization produces n-dodecane-in-water Pickering macroemulsions of 22-46 μm diameter. If the nanoparticles are present in sufficient excess, then subsequent processing using a high-pressure microfluidizer leads to the formation of Pickering nanoemulsions with a mean oil droplet diameter below 200 nm. The size of these Pickering nanoemulsions can be tuned by systematically varying the nanoparticle concentration, applied pressure, number of passes, and oil volume fraction. High-internal-phase emulsions can also be achieved by incr

SUBMITTER: Thompson KL 

PROVIDER: S-EPMC5677761 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature