Geographic Variation and US County Characteristics Associated With Rapid Kidney Function Decline.

ABSTRACT:

Introduction

Geographic variation in the prevalence of chronic kidney disease and incidence of end-stage renal disease has been previously reported. However, the geographic epidemiology of rapid estimated glomerular filtration rate (eGFR) decline has not been examined.

Methods

We built a longitudinal cohort of 2,107,570 US veterans to characterize the spatial epidemiology of and examine the associations between US county characteristics and rapid eGFR decline.

Results

There were 169,029 (8.02%) with rapid eGFR decline (defined as eGFR slope < -5 ml/min per 1.73 m²/year). The prevalence of rapid eGFR decline adjusted for age, race, gender, diabetes, and hypertension varied by county from 4.10%-6.72% in the lowest prevalence quintile to 8.41%-22.04% in the hi

SUBMITTER: Bowe B 

PROVIDER: S-EPMC5678675 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature