The MATEX cohort - a Finnish population register birth cohort to study health effects of prenatal exposures.

ABSTRACT:

Background

The prevalence of chronic diseases, such as immune, neurobehavioral, and metabolic disorders has increased in recent decades. According to the concept of Developmental Origin of Health and Disease (DOHaD), developmental factors associated with environmental exposures and maternal lifestyle choices may partly explain the observed increase. Register-based epidemiology is a prime tool to investigate the effects of prenatal exposures over the whole life course. Our aim is to establish a Finnish register-based birth cohort, which can be used to investigate various (prenatal) exposures and their effects during the whole life course with first analyses focusing on maternal smoking and air pollution. In this paper we (i) review previous studies to identify knowledge gaps and ove

SUBMITTER: Rumrich IK 

PROVIDER: S-EPMC5678812 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature