Human papillomavirus in semen and the risk for male infertility: a systematic review and meta-analysis.

ABSTRACT:

Background

Human papillomavirus (HPV) is one of the most prevalent sexually transmitted viruses. Despite the increasing evidence of HPV prevalence in semen, the worldwide distribution of HPV types in semen and risk for male infertility remain inconclusive.

Methods

Four electronic databases were searched for English language studies conducted between January 1990 and December 2016 that reported HPV DNA prevalence in semen. Based on the PRISMA guidelines, HPV prevalence was estimated among general population and fertility clinic attendees, respectively, and heterogeneity testing was performed using Cochran's Q and I ² statistics. The association between HPV positivity and male infertility was evaluated by a meta-analysis of case-control studies.

Results

A tot

SUBMITTER: Lyu Z 

PROVIDER: S-EPMC5679371 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature