Circulating Lipids and Acute Pain Sensitization: An Exploratory Analysis.

ABSTRACT: BACKGROUND:In individuals with low back pain, higher lipid levels have been documented and were associated with increased risk for chronic low back pain. OBJECTIVES:The purpose of this research was to identify plasma lipids that discriminate participants with acute low back pain with or without pain sensitization as measured by quantitative sensory testing. METHODS:This exploratory study was conducted as part of a larger parent randomized controlled trial. A cluster analysis of 30 participants with acute low back pain revealed two clusters: one with signs of peripheral and central sensitivity to mechanical and thermal stimuli and the other with an absence of peripheral and central sensitivity. Lipid levels were extracted from plasma and measured using mass spectroscopy. RESULTS:Triacylglyc

SUBMITTER: Starkweather A 

PROVIDER: S-EPMC5679413 | biostudies-literature | 2017 Nov/Dec

REPOSITORIES: biostudies-literature