Possible UIP pattern on high-resolution computed tomography is associated with better survival than definite UIP in IPF patients.

ABSTRACT:

Background

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing lung disease of unknown etiology. Inter-society consensus guidelines on IPF diagnosis and management outline radiologic patterns including definite usual interstitial pneumonia (UIP), possible UIP, and inconsistent with UIP. We evaluate these diagnostic categories as prognostic markers among patients with IPF.

Methods

Included subjects had biopsy-proven UIP, a multidisciplinary team diagnosis of IPF, and a baseline high-resolution computed tomography (HRCT). Thoracic radiologists assigned the radiologic pattern and documented the presence and extent of specific radiologic findings. The outcome of interest was lung transplant-free survival.

Results

IPF patients with a possible UIP pattern on HRCT

SUBMITTER: Salisbury ML 

PROVIDER: S-EPMC5679475 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature