Phenotypic and Functional Characterization of Circulatory, Splenic, and Hepatic NK Cells in Simian Immunodeficiency Virus-Controlling Macaques.
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ABSTRACT:
SUBMITTER: Vargas-Inchaustegui DA
PROVIDER: S-EPMC5679748 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Phenotypic and Functional Characterization of Circulatory, Splenic, and Hepatic NK Cells in Simian Immunodeficiency Virus-Controlling Macaques.
Vargas-Inchaustegui Diego A DA Helmold Hait Sabrina S Chung Hye Kyung HK Narola Jigna J Hoang Tanya T Robert-Guroff Marjorie M
Journal of immunology (Baltimore, Md. : 1950) 20170925 9
NK cells are key components of the immune system because of their rapid response potential and their ability to mediate cytotoxic and immunomodulatory functions. Additionally, NK cells have recently been shown to persist for long periods in vivo and to have the capacity to establish immunologic memory. In the current study, we assessed the phenotype and function of circulatory and tissue-resident NK cells in a unique cohort of SIV-controlling rhesus macaques that maintained low to undetectable l ...[more]
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