Incorporating Tumor Characteristics to the American Joint Committee on Cancer Breast Cancer Staging System.

ABSTRACT:

Background

The American Joint Committee on Cancer (AJCC) breast cancer staging system provides important prognostic information. The recently published eighth edition incorporates biological markers and recommends the use of a complex "prognostic stage." In this study, we assessed the relationship between stage, breast cancer subtype, grade, and outcome in a large population-based cohort and evaluated a risk score system incorporating tumor characteristic to the AJCC anatomic staging system.

Materials and methods

Patients diagnosed with primary breast cancer stage I-IV between 2005-2008 were identified in the California Cancer Registry. For patients with stage I-III disease, pathologic stage was recorded. For patients with stage IV disease, clinical stage was utilized. Five-

SUBMITTER: Chavez-MacGregor M 

PROVIDER: S-EPMC5679819 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature