Quantitative single breath-hold renal arterial spin labeling imaging at 7T.

ABSTRACT:

Purpose

To evaluate the feasibility of quantitative single breath-hold renal arterial spin labeling (ASL) imaging at 7T.

Methods

A single-shot fast spin echo FAIR (flow-sensitive alternating inversion recovery) method was used to perform two studies. First, a multi-delay perfusion study was performed to estimate the spin labeling temporal bolus width achievable with a local transceiver array coil at 7T. Second, with a conservatively defined bolus width, a quantitative perfusion study was performed using the single subtraction approach. To address issues of B1+ inhomogeneity/efficiency and excessive short-term specific absorption rates, various strategies were used, such as dynamic radiofrequency shimming and optimization.

Results

A conservative temporal bolus width of

SUBMITTER: Li X 

PROVIDER: S-EPMC5680158 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature