Identification of selection signals by large-scale whole-genome resequencing of cashmere goats.

ABSTRACT: Inner Mongolia and Liaoning cashmere goats are two outstanding Chinese multipurpose breeds that adapt well to the semi-arid temperate grassland. These two breeds are characterized by their soft cashmere fibers, thus making them great models to identify genomic regions that are associated with cashmere fiber traits. Whole-genome sequencing of 70 cashmere goats produced more than 5.52 million single-nucleotide polymorphisms and 710,600 short insertions and deletions. Further analysis of these genetic variants showed some population-specific molecular markers for the two cashmere goat breeds that are otherwise phenotypically similar. By analyzing F _ST and θ_π outlier values, we identified 135 genomic regions that were associated with cashmere fiber traits within the cashm

SUBMITTER: Li X 

PROVIDER: S-EPMC5680388 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature