Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells.

ABSTRACT: A highly sensitive microfluidic system to capture circulating tumor cells from whole blood of cancer patients is presented. The device incorporates graphene oxide into a thermoresponsive polymer film to serve as the first step of an antibody functionalization chemistry. By decreasing the temperature, captured cells may be released for subsequent analysis.

SUBMITTER: Yoon HJ 

PROVIDER: S-EPMC5680542 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature