Effective population sizes of a major vector of human diseases, Aedes aegypti.

ABSTRACT: The effective population size (N_e ) is a fundamental parameter in population genetics that determines the relative strength of selection and random genetic drift, the effect of migration, levels of inbreeding, and linkage disequilibrium. In many cases where it has been estimated in animals, N_e is on the order of 10%-20% of the census size. In this study, we use 12 microsatellite markers and 14,888 single nucleotide polymorphisms (SNPs) to empirically estimate N_e in Aedes aegypti, the major vector of yellow fever, dengue, chikungunya, and Zika viruses. We used the method of temporal sampling to estimate N_e on a global dataset made up of 46 samples of Ae. aegypti that included mu

SUBMITTER: Saarman NP 

PROVIDER: S-EPMC5680635 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature